S5T (p.Ser5Thr) variant of SHMT2 (P34897)
S5T (p.Ser5Thr) in SHMT2 (P34897) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
S5T (p.Ser5Thr) variant details
- p.Ser5Thr
- gnomAD 12-57229791-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.138
- REVEL 0.06
- CADD 13.90
- PolyPhen-2 0.00
- SIFT 0.20
- Population evidence available
- Structural context available
- Literature evidence available