S29R (p.Ser29Arg) variant of SHMT2 (P34897)
S29R (p.Ser29Arg) in SHMT2 (P34897) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
S29R (p.Ser29Arg) variant details
- p.Ser29Arg
- ExAC rs778622265
- TOPMed rs778622265
- gnomAD rs778622265
- Missense
- Variant Prioritization Score for Impact Estimate 0.187
- REVEL 0.04
- CADD 22.10
- PolyPhen-2 0.00
- SIFT 0.09
- Most common in the Non-Finnish European population (allele frequency 0.00024)
- Structural context available