S29G (p.Ser29Gly) variant of SHMT2 (P34897)
S29G (p.Ser29Gly) in SHMT2 (P34897) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
S29G (p.Ser29Gly) variant details
- p.Ser29Gly
- ExAC rs778622265
- TOPMed rs778622265
- gnomAD rs778622265
- Missense
- Variant Prioritization Score for Impact Estimate 0.182
- REVEL 0.04
- CADD 21.30
- PolyPhen-2 0.00
- SIFT 0.16
- Most common in the African/African-American population (allele frequency 0.00027)
- Structural context available