R11P (p.Arg11Pro) variant of SHMT2 (P34897)
R11P (p.Arg11Pro) in SHMT2 (P34897) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
R11P (p.Arg11Pro) variant details
- p.Arg11Pro
- gnomAD rs1234551409
- Missense
- Variant Prioritization Score for Impact Estimate 0.289
- REVEL 0.19
- CADD 22.40
- PolyPhen-2 0.30
- SIFT 0.01
- Most common in the HGDP:TUJIA population (allele frequency 0.05)
- Structural context available