L88L (p.Leu88Leu) variant of SHMT2 (P34897)
L88L (p.Leu88Leu) in SHMT2 (P34897) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
L88L (p.Leu88Leu) variant details
- p.Leu88Leu
- gnomAD 12-57231511-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.312
- CADD 12.30
- Most common in the Middle Eastern population (allele frequency 0.001)
- Structural context available
- Literature evidence available