L85P (p.Leu85Pro) variant of SHMT2 (P34897)
L85P (p.Leu85Pro) in SHMT2 (P34897) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data, published literature, and structural context.
L85P (p.Leu85Pro) variant details
- p.Leu85Pro
- gnomAD 12-57231503-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.659
- REVEL 0.64
- CADD 31.00
- PolyPhen-2 0.96
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available