L6F (p.Leu6Phe) variant of SHMT2 (P34897)
L6F (p.Leu6Phe) in SHMT2 (P34897) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data, published literature, and structural context.
L6F (p.Leu6Phe) variant details
- p.Leu6Phe
- gnomAD 12-57229796-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.131
- REVEL 0.03
- CADD 7.48
- PolyPhen-2 0.00
- SIFT 0.11
- Population evidence available
- Structural context available
- Literature evidence available