G37E (p.Gly37Glu) variant of SHMT2 (P34897)
G37E (p.Gly37Glu) in SHMT2 (P34897) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
G37E (p.Gly37Glu) variant details
- p.Gly37Glu
- gnomAD 12-57230879-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.289
- REVEL 0.06
- CADD 18.80
- PolyPhen-2 0.00
- SIFT 1.00
- Population evidence available
- Structural context available
- Literature evidence available