E63E (p.Glu63Glu) variant of SHMT2 (P34897)
E63E (p.Glu63Glu) in SHMT2 (P34897) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
E63E (p.Glu63Glu) variant details
- p.Glu63Glu
- rs866950450
- gnomAD 12-57230958-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.303
- CADD 12.10
- Most common in the Middle Eastern population (allele frequency 0.001)
- Structural context available
- Literature evidence available