V171L (p.Val171Leu) variant of SHANK3 (Q9BYB0)

V171L (p.Val171Leu) in SHANK3 (Q9BYB0) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as uncertain significance in the context of not provided. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes structural context.

V171L (p.Val171Leu) variant details