G52E (p.Gly52Glu) variant of SHANK3 (Q9BYB0)

G52E (p.Gly52Glu) in SHANK3 (Q9BYB0) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as uncertain significance in the context of Phelan-McDermid syndrome. The record also includes published literature and structural context.

G52E (p.Gly52Glu) variant details