G643R (p.Gly643Arg) variant of SHANK2 (Q9UPX8)

G643R (p.Gly643Arg) in SHANK2 (Q9UPX8) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as likely pathogenic in the context of Autism, susceptibility to, 17.

G643R (p.Gly643Arg) variant details