S36T (p.Ser36Thr) variant of SH2D1A (SH2 domain-containing protein 1A)
S36T (p.Ser36Thr) in SH2D1A (SH2 domain-containing protein 1A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data, published literature, and structural context.
S36T (p.Ser36Thr) variant details
- p.Ser36Thr
- gnomAD X-124346749-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.479
- REVEL 0.46
- MetaLR 0.84
- MetaSVM 0.59
- CADD 17.50
- PolyPhen-2 0.03
- SIFT 0.41
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available
- Literature evidence available