S27G (p.Ser27Gly) variant of SH2B3 (SH2B adapter protein 3)
S27G (p.Ser27Gly) in SH2B3 (SH2B adapter protein 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes structural context.
S27G (p.Ser27Gly) variant details
- p.Ser27Gly
- Ensembl rs2135546943
- Missense
- Variant Prioritization Score for Impact Estimate 0.163
- REVEL 0.11
- ESM-1b 0.00
- AlphaMissense 0.09
- MetaLR 0.10
- MetaSVM -1.02
- SIFT 0.32
- Structural context available