P23P (p.Pro23Pro) variant of SH2B3 (SH2B adapter protein 3)
P23P (p.Pro23Pro) in SH2B3 (SH2B adapter protein 3) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data, published literature, and structural context.
P23P (p.Pro23Pro) variant details
- p.Pro23Pro
- rs1435193343
- gnomAD 12-111418214-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.103
- CADD 3.09
- Most common in the African/African-American population (allele frequency 7.2e-05)
- Structural context available
- Literature evidence available