P11P (p.Pro11Pro) variant of SH2B3 (SH2B adapter protein 3)
P11P (p.Pro11Pro) in SH2B3 (SH2B adapter protein 3) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data, published literature, and structural context.
P11P (p.Pro11Pro) variant details
- p.Pro11Pro
- gnomAD 12-111418178-C-G
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.113
- CADD 4.51
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available
- Literature evidence available