M10L (p.Met10Leu) variant of SFTPC (Surfactant protein C)
M10L (p.Met10Leu) in SFTPC (Surfactant protein C) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
M10L (p.Met10Leu) variant details
- p.Met10Leu
- ExAC rs773026639
- gnomAD rs773026639
- Missense
- Variant Prioritization Score for Impact Estimate 0.498
- CADD 22.40
- PolyPhen-2 0.00
- SIFT 0.27
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available