I26T (p.Ile26Thr) variant of SFTPC (Surfactant protein C)
I26T (p.Ile26Thr) in SFTPC (Surfactant protein C) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data and structural context.
I26T (p.Ile26Thr) variant details
- p.Ile26Thr
- ExAC rs777139008
- gnomAD rs777139008
- Missense
- Variant Prioritization Score for Impact Estimate 0.645
- CADD 26.60
- PolyPhen-2 0.81
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available