G25S (p.Gly25Ser) variant of SFTPC (Surfactant protein C)
G25S (p.Gly25Ser) in SFTPC (Surfactant protein C) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
G25S (p.Gly25Ser) variant details
- p.Gly25Ser
- ExAC rs768626980
- gnomAD rs768626980
- Missense
- Variant Prioritization Score for Impact Estimate 0.168
- CADD 13.50
- PolyPhen-2 0.26
- SIFT 0.26
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available