G25D (p.Gly25Asp) variant of SFTPC (Surfactant protein C)
G25D (p.Gly25Asp) in SFTPC (Surfactant protein C) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
G25D (p.Gly25Asp) variant details
- p.Gly25Asp
- TOPMed rs1827790324
- Missense
- Variant Prioritization Score for Impact Estimate 0.464
- CADD 21.30
- PolyPhen-2 0.52
- SIFT 0.13
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available