G35V (p.Gly35Val) variant of SETBP1 (SET-binding protein)
G35V (p.Gly35Val) in SETBP1 (SET-binding protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
G35V (p.Gly35Val) variant details
- p.Gly35Val
- ExAC rs748268960
- TOPMed rs748268960
- gnomAD rs748268960
- Missense
- Variant Prioritization Score for Impact Estimate 0.521
- CADD 25.10
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available