V65M (p.Val65Met) variant of SERPINE1 (P05121)
V65M (p.Val65Met) in SERPINE1 (P05121) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data and structural context.
V65M (p.Val65Met) variant details
- p.Val65Met
- ExAC rs768436491
- TOPMed rs768436491
- gnomAD rs768436491
- Missense
- Variant Prioritization Score for Impact Estimate 0.679
- REVEL 0.59
- CADD 28.50
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available