V65L (p.Val65Leu) variant of SERPINE1 (P05121)
V65L (p.Val65Leu) in SERPINE1 (P05121) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
V65L (p.Val65Leu) variant details
- p.Val65Leu
- ExAC rs768436491
- TOPMed rs768436491
- gnomAD rs768436491
- Missense
- Variant Prioritization Score for Impact Estimate 0.611
- REVEL 0.49
- CADD 24.70
- PolyPhen-2 0.79
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available