V65A (p.Val65Ala) variant of SERPINE1 (P05121)
V65A (p.Val65Ala) in SERPINE1 (P05121) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
V65A (p.Val65Ala) variant details
- p.Val65Ala
- ExAC rs781150795
- gnomAD rs781150795
- Missense
- Variant Prioritization Score for Impact Estimate 0.47
- REVEL 0.35
- CADD 24.90
- PolyPhen-2 0.64
- SIFT 0.13
- Most common in the Latino/Admixed American population (allele frequency 4.5e-05)
- Structural context available