V55M (p.Val55Met) variant of SERPINE1 (P05121)
V55M (p.Val55Met) in SERPINE1 (P05121) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and structural context.
V55M (p.Val55Met) variant details
- p.Val55Met
- TOPMed rs1384573586
- gnomAD rs1384573586
- Missense
- Variant Prioritization Score for Impact Estimate 0.546
- REVEL 0.41
- CADD 22.00
- PolyPhen-2 0.20
- SIFT 0.04
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available