V55E (p.Val55Glu) variant of SERPINE1 (P05121)
V55E (p.Val55Glu) in SERPINE1 (P05121) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.79 / 1. The record also includes population frequency data, published literature, and structural context.
V55E (p.Val55Glu) variant details
- p.Val55Glu
- gnomAD 7-101128557-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.786
- REVEL 0.86
- CADD 32.00
- PolyPhen-2 0.97
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available