V40A (p.Val40Ala) variant of SERPINE1 (P05121)
V40A (p.Val40Ala) in SERPINE1 (P05121) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
V40A (p.Val40Ala) variant details
- p.Val40Ala
- gnomAD rs1290883786
- Missense
- Variant Prioritization Score for Impact Estimate 0.598
- REVEL 0.58
- CADD 25.40
- PolyPhen-2 0.36
- SIFT 0.04
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available