V31M (p.Val31Met) variant of SERPINE1 (P05121)
V31M (p.Val31Met) in SERPINE1 (P05121) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
V31M (p.Val31Met) variant details
- p.Val31Met
- 1000Genomes rs141347752
- ESP rs141347752
- ExAC rs141347752
- TOPMed rs141347752
- Missense
- Variant Prioritization Score for Impact Estimate 0.211
- REVEL 0.13
- CADD 20.30
- PolyPhen-2 0.37
- SIFT 0.04
- Most common in the HGDP:PALESTINIAN population (allele frequency 0.039)
- Structural context available