V31L (p.Val31Leu) variant of SERPINE1 (P05121)
V31L (p.Val31Leu) in SERPINE1 (P05121) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
V31L (p.Val31Leu) variant details
- p.Val31Leu
- 1000Genomes rs141347752
- ESP rs141347752
- ExAC rs141347752
- TOPMed rs141347752
- Missense
- Variant Prioritization Score for Impact Estimate 0.198
- REVEL 0.15
- CADD 11.30
- PolyPhen-2 0.02
- SIFT 0.79
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available