V24L (p.Val24Leu) variant of SERPINE1 (P05121)
V24L (p.Val24Leu) in SERPINE1 (P05121) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data, published literature, and structural context.
V24L (p.Val24Leu) variant details
- p.Val24Leu
- gnomAD 7-101128463-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.114
- REVEL 0.13
- CADD 0.22
- PolyPhen-2 0.00
- SIFT 0.90
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available