V24A (p.Val24Ala) variant of SERPINE1 (P05121)
V24A (p.Val24Ala) in SERPINE1 (P05121) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
V24A (p.Val24Ala) variant details
- p.Val24Ala
- ExAC rs753201992
- TOPMed rs753201992
- gnomAD rs753201992
- Missense
- Variant Prioritization Score for Impact Estimate 0.111
- REVEL 0.12
- CADD 5.71
- PolyPhen-2 0.00
- SIFT 0.46
- Most common in the Latino/Admixed American population (allele frequency 0.00016)
- Structural context available