T8T (p.Thr8Thr) variant of SERPINE1 (P05121)
T8T (p.Thr8Thr) in SERPINE1 (P05121) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
T8T (p.Thr8Thr) variant details
- p.Thr8Thr
- gnomAD 7-101128417-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.235
- CADD 8.95
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available
- Literature evidence available