S58L (p.Ser58Leu) variant of SERPINE1 (P05121)
S58L (p.Ser58Leu) in SERPINE1 (P05121) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.91 / 1. The record also includes population frequency data, published literature, and structural context.
S58L (p.Ser58Leu) variant details
- p.Ser58Leu
- gnomAD 7-101128566-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.912
- REVEL 0.97
- CADD 32.00
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available