S29F (p.Ser29Phe) variant of SERPINE1 (P05121)
S29F (p.Ser29Phe) in SERPINE1 (P05121) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
S29F (p.Ser29Phe) variant details
- p.Ser29Phe
- TOPMed rs1796153015
- gnomAD rs1796153015
- Missense
- Variant Prioritization Score for Impact Estimate 0.181
- REVEL 0.15
- CADD 7.46
- PolyPhen-2 0.38
- SIFT 0.71
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available