R41K (p.Arg41Lys) variant of SERPINE1 (P05121)
R41K (p.Arg41Lys) in SERPINE1 (P05121) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
R41K (p.Arg41Lys) variant details
- p.Arg41Lys
- ExAC rs768221689
- Missense
- Variant Prioritization Score for Impact Estimate 0.263
- REVEL 0.21
- CADD 16.70
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available