Q45R (p.Gln45Arg) variant of SERPINE1 (P05121)
Q45R (p.Gln45Arg) in SERPINE1 (P05121) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, published literature, and structural context.
Q45R (p.Gln45Arg) variant details
- p.Gln45Arg
- gnomAD 7-101128527-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.383
- REVEL 0.36
- CADD 24.70
- PolyPhen-2 0.17
- SIFT 0.04
- Population evidence available
- Structural context available
- Literature evidence available