P5T (p.Pro5Thr) variant of SERPINE1 (P05121)
P5T (p.Pro5Thr) in SERPINE1 (P05121) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
P5T (p.Pro5Thr) variant details
- p.Pro5Thr
- gnomAD rs1302913603
- Missense
- Variant Prioritization Score for Impact Estimate 0.179
- REVEL 0.13
- CADD 9.31
- PolyPhen-2 0.00
- SIFT 0.44
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available