P59T (p.Pro59Thr) variant of SERPINE1 (P05121)
P59T (p.Pro59Thr) in SERPINE1 (P05121) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.82 / 1. The record also includes population frequency data and structural context.
P59T (p.Pro59Thr) variant details
- p.Pro59Thr
- TOPMed rs1562851610
- Missense
- Variant Prioritization Score for Impact Estimate 0.82
- REVEL 0.84
- CADD 26.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available