P59L (p.Pro59Leu) variant of SERPINE1 (P05121)
P59L (p.Pro59Leu) in SERPINE1 (P05121) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.81 / 1. The record also includes population frequency data and structural context.
P59L (p.Pro59Leu) variant details
- p.Pro59Leu
- gnomAD rs1468978490
- Missense
- Variant Prioritization Score for Impact Estimate 0.809
- REVEL 0.81
- CADD 29.60
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available