P28S (p.Pro28Ser) variant of SERPINE1 (P05121)
P28S (p.Pro28Ser) in SERPINE1 (P05121) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
P28S (p.Pro28Ser) variant details
- p.Pro28Ser
- TOPMed rs1213710187
- gnomAD rs1213710187
- Missense
- Variant Prioritization Score for Impact Estimate 0.144
- REVEL 0.11
- CADD 7.60
- PolyPhen-2 0.00
- SIFT 0.34
- Most common in the East Asian population (allele frequency 0.0001)
- Structural context available