P28A (p.Pro28Ala) variant of SERPINE1 (P05121)
P28A (p.Pro28Ala) in SERPINE1 (P05121) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
P28A (p.Pro28Ala) variant details
- p.Pro28Ala
- TOPMed rs1213710187
- gnomAD rs1213710187
- Missense
- Variant Prioritization Score for Impact Estimate 0.144
- REVEL 0.13
- CADD 5.28
- PolyPhen-2 0.00
- SIFT 0.40
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available