M68V (p.Met68Val) variant of SERPINE1 (P05121)
M68V (p.Met68Val) in SERPINE1 (P05121) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
M68V (p.Met68Val) variant details
- p.Met68Val
- TOPMed rs1172504400
- gnomAD rs1172504400
- Missense
- Variant Prioritization Score for Impact Estimate 0.508
- REVEL 0.55
- CADD 22.60
- PolyPhen-2 0.34
- SIFT 0.09
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available