M68T (p.Met68Thr) variant of SERPINE1 (P05121)
M68T (p.Met68Thr) in SERPINE1 (P05121) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.80 / 1. The record also includes population frequency data and structural context.
M68T (p.Met68Thr) variant details
- p.Met68Thr
- ExAC rs769345666
- gnomAD rs769345666
- Missense
- Variant Prioritization Score for Impact Estimate 0.798
- REVEL 0.91
- CADD 26.50
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the South Asian population (allele frequency 0.00014)
- Structural context available