L7P (p.Leu7Pro) variant of SERPINE1 (P05121)
L7P (p.Leu7Pro) in SERPINE1 (P05121) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data, published literature, and structural context.
L7P (p.Leu7Pro) variant details
- p.Leu7Pro
- gnomAD 7-101128413-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.493
- REVEL 0.52
- CADD 17.70
- PolyPhen-2 0.20
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available