L71P (p.Leu71Pro) variant of SERPINE1 (P05121)
L71P (p.Leu71Pro) in SERPINE1 (P05121) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, published literature, and structural context.
L71P (p.Leu71Pro) variant details
- p.Leu71Pro
- gnomAD 7-101128605-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.382
- REVEL 0.38
- MetaLR 0.72
- MetaSVM -0.07
- CADD 22.70
- PolyPhen-2 0.93
- SIFT 0.08
- Population evidence available
- Structural context available
- Literature evidence available