L69F (p.Leu69Phe) variant of SERPINE1 (P05121)
L69F (p.Leu69Phe) in SERPINE1 (P05121) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.67 / 1. The record also includes population frequency data and structural context.
L69F (p.Leu69Phe) variant details
- p.Leu69Phe
- ExAC rs772860311
- TOPMed rs772860311
- gnomAD rs772860311
- Missense
- Variant Prioritization Score for Impact Estimate 0.665
- REVEL 0.64
- CADD 23.40
- PolyPhen-2 0.99
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available