L16F (p.Leu16Phe) variant of SERPINE1 (P05121)
L16F (p.Leu16Phe) in SERPINE1 (P05121) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
L16F (p.Leu16Phe) variant details
- p.Leu16Phe
- gnomAD rs1411224107
- Missense
- Variant Prioritization Score for Impact Estimate 0.254
- REVEL 0.25
- CADD 12.80
- PolyPhen-2 0.00
- SIFT 0.12
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available