H26Y (p.His26Tyr) variant of SERPINE1 (P05121)
H26Y (p.His26Tyr) in SERPINE1 (P05121) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
H26Y (p.His26Tyr) variant details
- p.His26Tyr
- gnomAD 7-101128469-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.219
- REVEL 0.16
- CADD 0.41
- PolyPhen-2 0.02
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available