H25Y (p.His25Tyr) variant of SERPINE1 (P05121)
H25Y (p.His25Tyr) in SERPINE1 (P05121) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data, published literature, and structural context.
H25Y (p.His25Tyr) variant details
- p.His25Tyr
- gnomAD 7-101128466-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.134
- REVEL 0.18
- CADD 0.01
- PolyPhen-2 0.00
- SIFT 0.85
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available