G39W (p.Gly39Trp) variant of SERPINE1 (P05121)
G39W (p.Gly39Trp) in SERPINE1 (P05121) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.84 / 1. The record also includes population frequency data and structural context.
G39W (p.Gly39Trp) variant details
- p.Gly39Trp
- TOPMed rs1246094084
- gnomAD rs1246094084
- Missense
- Variant Prioritization Score for Impact Estimate 0.843
- REVEL 0.85
- CADD 32.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 4.5e-05)
- Structural context available